It also usually means fear is about to set in. Fear of losing his freedom. Fear that you aren’t the one for him. The clonal amplification issue which could lead to high false positives has to a certain extent, been ameliorated in the microarray based detection method. 4C microarray approaches work by normalizing PCR amplified 4C data against PCR amplified genomic background, thus normalizing clonal amplifications; followed by applying a running mean algorithm to define clusters of increased hybridization signals relative to the surrounding genomic area4,16, hence enabling the detection of clusters indicating chromatin interactions. However, microarrays have a limited dynamic range and poor coverage of repetitive regions.
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Australia not only beat India, they thrashed them. Humiliated them. On a dry, turning pitch that should have suited India’s spinners, Steven Smith scored the only hundred of the match and Steve O’Keefe took as many wickets as R Ashwin and Ravindra Jadeja combined.
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